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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFHX3
All Species:
19.7
Human Site:
T2376
Identified Species:
54.17
UniProt:
Q15911
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15911
NP_008816.3
3703
404419
T2376
M
D
A
M
E
I
L
T
P
T
S
S
S
C
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102605
3690
403131
T2371
M
D
A
M
E
I
L
T
P
T
S
S
S
C
S
Dog
Lupus familis
XP_851092
3710
405366
T2385
M
D
A
M
E
I
L
T
P
T
S
S
S
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61329
3726
406551
T2385
A
M
E
I
L
T
P
T
S
S
S
C
S
T
P
Rat
Rattus norvegicus
XP_001076847
3720
406302
T2377
M
D
A
M
E
I
L
T
P
T
S
S
S
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509863
3710
407348
T2382
M
D
A
M
E
L
L
T
P
T
S
S
S
C
S
Chicken
Gallus gallus
O73590
3573
394529
V2303
M
D
A
S
D
Q
T
V
Y
K
N
C
T
V
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393785
2962
326678
Q1761
Q
Q
Q
Q
Q
Q
H
Q
Q
Q
Q
Q
Q
Q
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798150
3296
366823
P2094
S
P
Y
N
F
N
N
P
P
T
T
S
L
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.6
97
N.A.
93.8
94.1
N.A.
91.9
54.6
N.A.
N.A.
N.A.
N.A.
24.2
N.A.
24
Protein Similarity:
100
N.A.
98.9
97.9
N.A.
95.3
95.6
N.A.
94.4
68.1
N.A.
N.A.
N.A.
N.A.
39.2
N.A.
39.6
P-Site Identity:
100
N.A.
100
100
N.A.
20
100
N.A.
93.3
26.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
20
P-Site Similarity:
100
N.A.
100
100
N.A.
33.3
100
N.A.
100
46.6
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
67
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
23
0
56
0
% C
% Asp:
0
67
0
0
12
0
0
0
0
0
0
0
0
0
12
% D
% Glu:
0
0
12
0
56
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
0
45
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% K
% Leu:
0
0
0
0
12
12
56
0
0
0
0
0
12
12
0
% L
% Met:
67
12
0
56
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
12
12
0
0
0
12
0
0
0
0
% N
% Pro:
0
12
0
0
0
0
12
12
67
0
0
0
0
0
12
% P
% Gln:
12
12
12
12
12
23
0
12
12
12
12
12
12
12
12
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
0
12
0
0
0
0
12
12
67
67
67
0
67
% S
% Thr:
0
0
0
0
0
12
12
67
0
67
12
0
12
12
0
% T
% Val:
0
0
0
0
0
0
0
12
0
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
0
0
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _